20 Best Nsaid With Caffeine [2025]

Are you looking for the best Nsaid With Caffeine? Based on expert reviews, we ranked them. We've listed our top-ranked picks, including the top-selling Nsaid With Caffeine.

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1 GenCare - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets)... GenCare - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300...
2 Amazon Basic Care Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, 200 Count Amazon Basic Care Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, 200 Count
3 Safrel - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets)... Safrel - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300...
4 Rite Aid Extra Strength Pain Reliever, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100... Rite Aid Extra Strength Pain Reliever, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100...
5 BC Powder Fast Pain Relief Arthritis Aspirin (NSAID) & Caffeine 50 Count BC Powder Fast Pain Relief Arthritis Aspirin (NSAID) & Caffeine 50 Count
6 GoodSense Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, Migraine Relief, 24... GoodSense Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, Migraine Relief,...
7 Anacin- Fast Pain Relief (NSAID) With Caffeine -50 Tablets Per Box-Pack of 6 Anacin- Fast Pain Relief (NSAID) With Caffeine -50 Tablets Per Box-Pack of 6
8 Anacin Aspirin (NSAID) Caffeine Pain Reliever Aid, 100 Tablets Anacin Aspirin (NSAID) Caffeine Pain Reliever Aid, 100 Tablets
9 BC Stunts FREE BC Stunts FREE
10 The Best of B.C. The Best of B.C.
11 Right Remedies Extra Strength Headache Pain Relief, Acetaminophen with Aspirin (NSAID) and Caffeine,... Right Remedies Extra Strength Headache Pain Relief, Acetaminophen with Aspirin (NSAID) and...
12 Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
13 GoodSense Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count GoodSense Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
14 GenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg and Caffeine 65 mg (200... GenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg and Caffeine 65 mg (200...
15 BC Powder Pain Reliever, Cherry Flavor Dissolve Packs, 24 Individual Packets BC Powder Pain Reliever, Cherry Flavor Dissolve Packs, 24 Individual Packets
16 Rite Aid Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100 Count Caplets |... Rite Aid Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100 Count Caplets...
17 HealthA2Z Tension Headache Relief, Aspirin Free, Compare to Excedrin Active Ingredient, 200 Caplets HealthA2Z Tension Headache Relief, Aspirin Free, Compare to Excedrin Active Ingredient, 200 Caplets
18 Rite Aid Tension Headache Pain Reliever, Acetaminophen, 500 mg, 100 Coated Caplets | Tension... Rite Aid Tension Headache Pain Reliever, Acetaminophen, 500 mg, 100 Coated Caplets | Tension...
19 GoodSense Aspirin Pain Reliever & Fever Reducer (NSAID), 325 mg Coated Tablets, Temporarily Relieves... GoodSense Aspirin Pain Reliever & Fever Reducer (NSAID), 325 mg Coated Tablets, Temporarily...
20 Right Remedies Headache Relief, Extra Strength Geltabs, Pain Relief Acetaminophen with Aspirin... Right Remedies Headache Relief, Extra Strength Geltabs, Pain Relief Acetaminophen with Aspirin...
Bestseller No. 1
GenCare - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets)...
  • ✅ HEAD & BODY PAIN RELIEF - Each caplet of Extra Strength Headache Relief contains 250mg of Acetaminophen, 250mg of Aspirin (NSAID) and 65 mg of...
  • ✅ BULK SAVINGS - You and your family will always have effective over the counter relief with our family size 300 caplet value savings bottle. Always...
  • ✅ ACTS FAST - Headaches, migraines and pain can hit at the worst time. 65 mg of caffeine in each pill help energize you and restore mental focus so...
  • ✅ HELPS WITH ACHES & PAINS - Toothaches, menstrual cramps, arthritis, joint pain and more in one easy to swallow caplet. Adults and children 12...
  • ✅ 100% SATISFACTION GUARANTEE - Say goodbye to headaches and pain! GenCare backs up each bulk savings bottle of Extra Strength Headache Relief with...
Bestseller No. 2
Amazon Basic Care Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, 200 Count
  • ACTIVE INGREDIENTS: Amazon Basic Care Migraine Relief contains acetaminophen 250 mg, aspirin 250 mg (NSAID), and caffeine 65 mg; compare to the active...
  • MIGRAINE PAIN: The pain of migraine headaches can disrupt your lifestyle; Amazon Basic Care Migraine Relief caplets help to treat migraine pain so you...
  • COATED CAPLETS treat migraine headache pain; caplets are capsule-shaped tablets
  • FOR ADULTS: Amazon Basic Care Migraine Relief caplets treat migraine headaches in adults; use a 2-caplet dose for migraine pain relief; under 18 years...
  • GLUTEN FREE: This migraine relief medicine is gluten free
Bestseller No. 3
Safrel - Extra Strength Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets)...
  • ✅ ACTIVE INGREDIENT: The active ingredient in this product is Acetaminophen, Aspirin and Caffeine, it provides headache and pain relief. Compare...
  • ✅ COMPLETE AND FAST PAIN RELIEF – This extra-strength headache medicine also helps relieve other aches and pains, such as arthritis, muscles...
  • ✅ HELPS WITH HEADACHE & OTHER ACHES/PAIN: Provides relief from Headaches, Toothaches, menstrual cramps, arthritis, joint pain and more in one easy...
  • ✅ VALUE PACK SAVINGS: Each bottle of our pain relief medicine contains 300 total caplets to help you and your entire family find long-lasting relief...
  • ✅ 100% SATISFACTION GUARANTEE: Click Buy Now and get this Extra Strength Headache Relief formula to enjoy your day free from headache and other...
Bestseller No. 4
Rite Aid Extra Strength Pain Reliever, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100...
  • EXTRA STRENGTH: Rite Aid Extra Strength Pain Reliever Acetaminophen 250mg, Aspirin 250mg, & Caffeine 65mg is specifically formulated to relieve pain,...
  • CONTAINS CAFFEINE: Caffeine has been proven to help with migraines and tension headaches by opening the constricted blood vessels in your brain. Rite...
  • IBUPROFEN-FREE: Each caplet contains 250 mg of pain relieving, fever reducing aspirin, plus 250 mg acetaminophen, plus 65 mg caffeine. This migraine...
  • EASY-TO-SWALLOW COATED TABLET: Rite Aid Acetaminophen/Aspirin/Caffeine Pain Reliever comes in a coated tablet design that makes them easy to swallow....
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the...
SaleBestseller No. 5
BC Powder Fast Pain Relief Arthritis Aspirin (NSAID) & Caffeine 50 Count
  • Aspirin powder with caffeine
  • Temporarily relieves aches and pains due to minor arthritis pain
  • Contains a higher dose of aspirin than our Original Formula
  • On-the-go powder stick packs
  • 50 powders
Bestseller No. 6
GoodSense Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, Migraine Relief, 24...
  • ACTIVE INGREDIENTS: GoodSense Migraine Relief contains acetaminophen 250 mg, aspirin 250 mg (NSAID), and caffeine 65 mg; compare to the active...
  • MIGRAINE PAIN: The pain of migraine headaches can disrupt your lifestyle; GoodSense Migraine Relief caplets help to treat migraine pain so you can get...
  • COATED CAPLETS treat migraine headache pain; caplets are capsule-shaped tablets
  • FOR ADULTS: GoodSense Migraine Relief caplets treat migraine headaches in adults; use a 2-caplet dose for migraine pain relief; under 18 years of age,...
  • GLUTEN FREE: This migraine relief medicine is gluten free.
SaleBestseller No. 7
Anacin- Fast Pain Relief (NSAID) With Caffeine -50 Tablets Per Box-Pack of 6
  • Aspirin + Caffeine = Fast Pain Relief
  • Trusted, safe and effective
  • For minor aches and pains due to headache, muscular ache, back ache, toothache, menstrual cramps, a cold and arthritis
  • Nonsteroidal anti-inflammatory drug (NSAID)
  • Each box contains 50 coated tablets
Bestseller No. 9
BC Stunts FREE
  • The latest instalment in the internationally successful Bridge Constructor series!
  • Improved and simplified Construction Mode
  • Build ramps and drive vehicles across them yourself
  • Diverse levels with different objectives: collect stars, score target, reach the goal…
  • Delivery vans and dump trucks with cargo that wreaks havoc when coming loose, but is also useful to help you collect items
Bestseller No. 10
The Best of B.C.
  • Amazon Kindle Edition
  • Hart, Johnny (Author)
  • English (Publication Language)
  • 241 Pages - 11/23/2016 (Publication Date) - Titan (Publisher)
Bestseller No. 11
Right Remedies Extra Strength Headache Pain Relief, Acetaminophen with Aspirin (NSAID) and Caffeine,...
  • ✅ PAIN RELIEF: A family safe and effective solution of over-the-counter medication for a range of headache and body pain relief
  • ✅ USES: Helps to relieve minor aches and pains due to headache, cold, arthritis, muscle aches, toothache, menstrual and premenstrual cramps
  • ✅ FAST ACTING FORMULA: With two pain fighters as amplifiers 65mg of caffeine in each pill helps energize and restore mental focus. Avoid this...
  • ✅ RIGHT REMEDIES: A value purchase that saves you money
  • ✅ 100% SATISFACTION GUARANTEE – we know your family will love this product that comes with a tamper evident safety seal. Join thousands of happy...
Bestseller No. 12
Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
  • ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg....
  • PAIN RELIEF: Amazon Basic Care Migraine Relief Geltabs offer headache pain relief so you don't miss out on life's special moments
  • MIGRAINE TREATMENT: Just one dose helps to temporarily reduce headache pain caused by migraines
  • PAIN RELIEVER AND PAIN RELIEVER AID: Amazon Basic Care Migraine Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal...
  • GLUTEN FREE: These headache pain relief pills are gluten free
Bestseller No. 13
GoodSense Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
  • ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg....
  • PAIN RELIEF: GoodSense Migraine Relief Geltabs offer headache pain relief so you don't miss out on life's special moments
  • MIGRAINE TREATMENT: Just one dose helps to temporarily reduce headache pain caused by migraines
  • PAIN RELIEVER AND PAIN RELIEVER AID: GoodSense Migraine Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal...
  • GLUTEN FREE: These headache pain relief pills are gluten free
Bestseller No. 14
GenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg and Caffeine 65 mg (200...
  • ✅ EXTRA STRENGTH RELIEF - Reach for GenCare extra strength Tension Headache Relief when suffering from mild to severe headaches, tension pain and...
  • ✅ FULL BODY PAIN REMEDY - The potent combination of Acetaminophen (500mg) and Caffeine (65mg) isn't just for mild to severe headaches. It provides...
  • ✅ MENTAL FOCUS - Caffeine can help quickly restore energy levels and focus so you can get over the pain and back to being productive and at your...
  • ✅ FAMILY VALUE SIZE - Always be prepared with our ultra convenient 200 caplet bulk savings bottle. Save money and keep your family's medicine...
  • ✅ 100% SATISFACTION GUARANTEE - Enjoy fast and effective headache and muscle ache relief! GenCare backs up each bulk savings bottle of Tension...
Bestseller No. 15
BC Powder Pain Reliever, Cherry Flavor Dissolve Packs, 24 Individual Packets
  • BC Powder Cherry Pain Reliever works fast to temporarily relieve headaches, backaches, toothaches, muscle aches and menstrual cramps
  • Unique dual action powder formula works fast to relieve pain
  • Contains 845 mg Aspirin (NSAID) and 65 mg Caffeine
  • Great tasting cherry flavor is easy to swallow
  • Convenient, on-the-go stick packs for relief anytime or anywhere
Bestseller No. 16
Rite Aid Migraine Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg – 100 Count Caplets |...
  • TARGETED MIGRAINE PAIN RELIEF: Rite Aid Migraine Relief Acetaminophen 250mg, Aspirin 250mg, & Caffeine 65mg is specifically formulated to relieve...
  • CONTAINS CAFFEINE: Caffeine has been proven to help with migraines and tension headaches by opening the constricted blood vessels in your brain. Rite...
  • IBUPROFEN-FREE: Each caplet contains 250 mg of pain relieving, fever reducing aspirin, plus 250 mg acetaminophen, plus 65 mg caffeine. This migraine...
  • EASY-TO-SWALLOW COATED CAPLET: Rite Aid Acetaminophen/Aspirin/Caffeine Migraine Relief Pain Reliever comes in a coated caplet design that makes them...
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the...
SaleBestseller No. 17
HealthA2Z Tension Headache Relief, Aspirin Free, Compare to Excedrin Active Ingredient, 200 Caplets
  • Made In USA / Compare to Excedrin active ingredient.
  • It works by combining the power of Acetaminophen and Caffeine which work synergistically to provide fast relief for head, neck, and shoulder pain...
  • It is aspirin free and is gentler on your stomach than aspirin-based products.
  • Adults and children 12 years and over: take 2 caplets every 6 hours. Do not take more than 8 caplets in 24 hours. Children under 12 years of age: ask...
Bestseller No. 18
Rite Aid Tension Headache Pain Reliever, Acetaminophen, 500 mg, 100 Coated Caplets | Tension...
  • TARGETED PAIN RELIEF: Rite Aid's Acetaminophen 500mg Tension Headache Pain Reliever + caffeine is specifically formulated to relieve tension headaches...
  • CONTAINS CAFFEINE: Caffeine has been proven to help with tension headaches and migraine relief by opening the constricted blood vessels in your brain....
  • NO ASPIRIN: Each caplet contains 500 mg of pain relieving, fever reducing acetaminophen, plus 65 mg caffeine, without any aspirin. This aspirin-free,...
  • EASY-TO-SWALLOW COATED CAPLET: Rite Aid Acetaminophen 500mg Tension Headache Pain Reliever comes in a coated caplet design that makes them easy to...
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose us first for your everyday health and wellness needs. Our mission is to improve the health...
SaleBestseller No. 19
GoodSense Aspirin Pain Reliever & Fever Reducer (NSAID), 325 mg Coated Tablets, Temporarily Relieves...
  • ACTIVE INGREDIENT: The active ingredient is aspirin 325 mg, a regular strength nonsteroidal anti-inflammatory drug in coated tablets; compare to Bayer...
  • BENEFITS: Safe pain relief plus lifesaving benefits; talk to your doctor or other healthcare provider before using GoodSense Aspirin Tablets 325 mg,...
  • HEADACHE, ARTHRITIS AND MUSCLE PAIN can cause annoying discomfort any time of day; GoodSense Aspirin Tablets 325 mg contain a nonsteroidal...
  • CAFFEINE FREE AND DYE FREE: This product is gluten free, as well as caffeine free and dye free
  • ASPIRIN is in a class of analgesics, or pain relievers, called nonsteroidal anti-inflammatory drugs; use for adults and children 12 years and over
Bestseller No. 20
Right Remedies Headache Relief, Extra Strength Geltabs, Pain Relief Acetaminophen with Aspirin...
  • ✅ PAIN RELIEF: A family safe and effective solution of over-the-counter medication for a range of headache and body pain relief
  • ✅ USES: Helps to relieve minor aches and pains due to headache, cold, arthritis, muscle aches, toothache, menstrual and premenstrual cramps
  • ✅ FAST ACTING FORMULA: With two pain fighters as amplifiers 65mg of caffeine in each pill helps energize and restore mental focus. Avoid this...
  • ✅ RIGHT REMEDIES: A value purchase that saves you money
  • ✅ 100% SATISFACTION GUARANTEE – we know your family will love this product that comes with a tamper evident safety seal. Join thousands of happy...

Having trouble finding a great Nsaid With Caffeine?

This problem is well understood by us because we have gone through the entire Nsaid With Caffeine research process ourselves, which is why we have put together a comprehensive list of the best Nsaid With Caffeines available in the market today.

After hours of searching and using all the models on the market, we have found the best Nsaid With Caffeine for 2023. See our ranking below!

How Do You Buy The Best Nsaid With Caffeine?

Do you get stressed out thinking about shopping for a great Nsaid With Caffeine? Do doubts keep creeping into your mind?

We understand, because we’ve already gone through the whole process of researching Nsaid With Caffeine, which is why we have assembled a comprehensive list of the greatest Nsaid With Caffeine available in the current market. We’ve also come up with a list of questions that you probably have yourself.

John Harvards has done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for Nsaid With Caffeine that you consider buying. Your questions might include the following:

  • Is it worth buying an Nsaid With Caffeine?
  • What benefits are there with buying an Nsaid With Caffeine?
  • What factors deserve consideration when shopping for an effective Nsaid With Caffeine?
  • Why is it crucial to invest in any Nsaid With Caffeine, much less the best one?
  • Which Nsaid With Caffeine are good in the current market?
  • Where can you find information like this about Nsaid With Caffeine?

We’re convinced that you likely have far more questions than just these regarding Nsaid With Caffeine, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for Nsaid With Caffeine, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best-possible Nsaid With Caffeine. Make sure that you are only using trustworthy and credible websites and sources.

John Harvards provides an Nsaid With Caffeine buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information.

How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available Nsaid With Caffeine currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of Nsaid With Caffeine has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an Nsaid With Caffeine?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your Nsaid With Caffeine.
  5. Customer Ratings: Number ratings grade Nsaid With Caffeine objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their Nsaid With Caffeine.
  7. Product Quality: You don’t always get what you pay for with an Nsaid With Caffeine, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an Nsaid With Caffeine is should be an indication of how long it will work out for you.

John Harvards always remembers that maintaining Nsaid With Caffeine information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

If you think that anything we present here regarding Nsaid With Caffeine is irrelevant, incorrect, misleading, or erroneous, then please let us know promptly!

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FAQ:

Q: Does caffeine potentiate NSAIDs?

A: Because caffeine shifts the effect-compartment concentration-effect relation of NSAIDs to the left and this relationship is sigmoidal, there is no potentiation if the NSAID concentrations are too high or too low with respect to EC(50).

Q: Is caffeine better than ibuprofen for headaches?

A: Ibuprofen and caffeine administered together demonstrated significantly shorter times to meaningful improvement in headache relief than ibuprofen or placebo; significantly greater total analgesia than ibuprofen alone, caffeine alone, or placebo; and significantly greater peak relief than ibuprofen alone, caffeine alone, or placebo.

Q: What is the NNT of ibuprofen and caffeine?

A: For at least 50% of maximum pain relief, the NNT was 2.1 (95% confidence interval 1.8 to 2.5) for ibuprofen 200 mg + caffeine 100 mg (four studies, 334 participants) and 2.4 (1.9 to 3.1) for ibuprofen 100 mg + caffeine 100 mg (two studies, 200 participants) (moderate quality evidence).

Q: How effective is caffeine with ibuprofen 200 mg?

A: Ibuprofen 200 mg + caffeine 50 mg, n = 30 for efficacy Ibuprofen 200 mg + caffeine 100 mg, n = 30 for efficacy Ibuprofen 200 mg + caffeine 200 mg, n = 29 for efficacy Ibuprofen 200 mg, n = 31 for efficacy